Missouri Advances Unlimited Cannabis Research Licensing Program
Missouri prepares to offer unlimited cannabis research licenses as new rules enter public comment phase through May 31.

JEFFERSON CITY, MISSOURI β Missouri is advancing plans to establish an unlimited number of licenses for marijuana research, implementing provisions from the state’s 2022 recreational cannabis constitutional amendment.
The Missouri Division of Cannabis Regulation has submitted proposed rules to the Secretary of State that outline licensing requirements and procedures for cannabis research facilities. The rules detail what research licensees would be authorized to conduct and establish the application process for obtaining permits.
“Ultimately, it’s just exciting to make progress on marijuana research because we know that that’s been historically difficult,” said Rieka Yu, policy director for the division, which operates within the Missouri Department of Health and Senior Services.
Public Comment Period Opens
The proposed regulations will be published in the May 1 edition of the Missouri Register on the Secretary of State’s website. Citizens and stakeholders will have until May 31 to submit public feedback on the draft rules.
When Missouri voters approved recreational marijuana in 2022, the constitutional amendment included provisions allowing the state to create licenses to “facilitate scientific research or education.” However, administrative rules were required before the licensing program could begin operations.
Broad Research Opportunities Expected
Amy Moore, director of the Division of Cannabis Regulation, said the amendment’s language creates opportunities for diverse research initiatives beyond traditional medical studies.
“We’re all very interested in any research on cannabis and safety or its impact on the human body,” Moore said. “Certainly as a public health agency, we’re interested in health research, but it’s not limited to that. So it’ll be interesting to see what people want to propose once we get this established.”
Yu expressed particular interest in cultivation research, pointing to New York’s experience as a model. New York implemented marijuana research rules in 2023 and has since approved studies examining plant virus protection and the effects of different lighting on cannabis growth.
The Missouri program would allow researchers to study various aspects of cannabis, from health impacts and safety considerations to agricultural techniques and educational applications. Unlike commercial cannabis licenses, research permits would not be subject to numerical caps.
Implementation Timeline
The rule-making process represents the final regulatory step needed to activate the research licensing program authorized by Missouri’s constitutional amendment. Once public comments are reviewed and final rules are adopted, the state will begin accepting applications for research licenses.
The Division of Cannabis Regulation, housed within the Missouri Department of Health and Senior Services, will oversee the licensing and regulation of research facilities. The program aims to address historical barriers to cannabis research while maintaining appropriate oversight and safety standards.
Interested researchers, academic institutions, and other organizations will be able to apply for licenses once the rules are finalized following the public comment period.



